Customization: | Available |
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CAS No.: | 51-35-4 |
Formula: | C5h9no3 |
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Product Name L-Hydroxyproline
Alias Trans-4-Hydroxy-L-proline
Molecular Formula C5H9NO3
Molecular Weight 131.1313
CAS No. 51-35-4
Shelf Life 2 years
L-Hydroxyproline Basic information | |
Product Name: | L-Hydroxyproline |
CAS: | 51-35-4 |
MF: | C5H9NO3 |
MW: | 131.13 |
EINECS: | 200-091-9 |
Mol File: | 51-35-4.mol |
L-Hydroxyproline Chemical Properties | |
Melting point | 273 °C (dec.)(lit.) |
alpha | -75.5 º (c=5, H2O) |
Boiling point | 242.42°C (rough estimate) |
density | 1.3121 (rough estimate) |
vapor density | 4.5 (vs air) |
refractive index | -75.5 ° (C=4, H2O) |
storage temp. | Store below +30°C. |
solubility | H2O: 50 mg/mL |
form | Crystals or Crystalline Powder |
pka | 1.82, 9.66(at 25ºC) |
color | White |
PH | 5.5-6.5 (50g/l, H2O, 20ºC) |
Odor | Odorless |
optical activity | [α]25/D 75.6°, c = 1 in H2O |
Water Solubility | 357.8 g/L (20 º C) |
Merck | 144,840 |
BRN | 471933 |
InChIKey | PMMYEEVYMWASQN-DMTCNVIQSA-N |
CAS DataBase Reference | 51-35-4(CAS DataBase Reference) |
NIST Chemistry Reference | Hydroxyproline(51-35-4) |
EPA Substance Registry System | trans-4-Hydroxy-L-proline (51-35-4) |
Brief introduction
L-hydroxyproline is a common non-standard protein amino acid. As the main raw material of the antiviral drug atazanavir, it has high application value. Hydroxyproline is generally used as a food additive (used as a sweetener in relatively small amounts), while in medicine, it is used as an intermediate in the Penam side chain in relatively large amounts.
Application
L-hydroxyproline is a natural component of animal structural proteins, such as collagen and Elastin. Several microorganisms producing proline trans-4- and cis 3-hydroxylase have been discovered and used for industrial production of trans-4- and cis 3-hydroxy-L-proline.
Chemical property
White flaky crystalline or crystalline powder. The unique sweetness in bitterness can improve the flavor and quality of fruit juice drinks, cool drinks, etc. It has a special flavor and can be used as a fragrance ingredient. Melting point 274 ºC (decomposition). Easily soluble in water (25 ºC, 36.1%), slightly soluble in ethanol.
Purpose
Flavor enhancer; Nutritional fortifiers. Fragrance. Mainly used for juice, refreshing beverages, nutritional beverages, etc.
Packing:
25kg/drum
Storage:
Store in tightly closed original container, protected from light, in a dry place.
Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
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