Product Description
| Product name |
Levocetirizine Dihydrochloride |
| Appearance |
White powder |
| CAS NO. |
130018-87-0 |
| MF |
C21H27Cl3N2O3 |
| MW |
461.808 |
Product Name: Levocetirizine dihydrochloride
Synonyms: LEVOCETIRIZINE 2HCL;LEVOCETIRIZINE DIHCL;LEVOCETIRIZINE DIHYDROCHLORIDE;LEVOCETIRIZINE HCL;LEVOCETRIZINE DIHYDROCHLORIDE;[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride;[2-[4-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]-ACETIC ACID 2HCL;(R)-Cetirizine (hydrochloride)
CAS: 130018-87-0
MF: C21H27Cl3N2O3
MW: 461.81
EINECS: 641-093-3
Product Categories: Antibiotics;Levocitirizine 2HCl;API's;Levocetirizine;Histamine receptor;API
Mol File: 130018-87-0.mol
Levocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. This R-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H1-receptors.
Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .
Usage:It is used to treat seasonal allergic rhinitis, perennial allergic rhinitis, allergic conjunctivitis, and chronic idiopathic urticaria.
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