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Product Name:Ketoconazole Powder
CAS:65277-42-1
Formula:C26H28Cl2N4O4
EINECS:265-667-4
Molecular Weight:531.44
Assay:98%min
Appearance:White or off-white crystal Powder
| Items | Specification | Results |
| Appearance | White or almost white crystalline powder | Confirms |
| Practically insoluble in water, freely | ||
| soluble in methylene chloride, soluble | ||
| in methanol, sparingly soluble in alcohol. | ||
| Identification | IR | Confirms |
| Melting range, °C | 148.0~152.0 | 148.0~150. |
| Specific Rotation | -1.0o~+1.0o | 0o |
| Loss on Drying, % | ≤ 0.50 | 0.1 |
| Residue on Ignition, % | ≤ 0.10 | 0.06 |
| Heavy Metals, % | ≤ 0.002 | < 0.002 |
| Chromatographic purity, % | ≤ 2.0 | Confirms |
| Residue Solvent, % | ||
| Acetoacetate | ≤ 0.50 | 0.3 |
| Dimethyl sulfoxide | ≤ 0.50 | 0 |
| Bacteria | Not more than 10 per g | Confirms |
| Mold & yeast | None-detected | Confirms |
| Assay, % | 98.0~102.0 | 99.2 |
Ketoconazole shampoo in conjunction with an oral 5α-reductase inhibitor has been used off label to treat
and rogenic alopecia.
The antifungal properties of ketoconazole reduce scalp microflora and consequently may reduce follicular inflammation that contributes to alopecia.Limited clinical studies suggest ketoconazole shampoo used either alone or in combination with other treatments may be useful in reducing hair loss. At least one study has been performed showing that ketoconazole may be useful in temporarily reducing erectile function in postoperative penile surgery patients.
Veterinary use
Ketoconazole is also sometimes prescribed by veterinarians for use on pets, often as unflavored tablets that may need to be cut to smaller size for correct dosage.
Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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