USP Bp Verapamil Hydrochloride CAS No 23313-68-0 Verapamil HCl

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: 23313-68-0
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• Purity: >99%
• Molecular Weight: 491.063
• Boiling Point: 586.1 C at 760 Mmhg
• Melting Point: 140-144 C
• Flash Point: 308.3 C
• Transport Package: 25kg
• Specification: standard
• Trademark: QSC
• Origin: China
• Production Capacity: 50000000

Product Description

 

Verapamil hydrochloride is an α-adrenergic receptor (α-AR) antagonist and calcium channel protein inhibitor that blocks the L-type Ca2+ channels in smooth and cardiac muscle cells. Verapamil is an antiarrhythmic agent and vasodilator known to reduce the renal clearance of dig oxin and induce apoptosis in primary and metastatic colon adenocarcinoma human cell lines in vitro. It has been observed that verapamil can induce currents by itself, presumably by acting on the potassium and chloride leakage. Verapamil has also been used as an inhibitor of drug efflux pump proteins such as Mdr (P-glycoprotein). Verapamil is a substrate of CYP3A4 and CYP2C6.

Melting point: 140-144º C
Description: White crystalline powder
Content(HPLC): ≥ 99.0%
Loss On Drying: ≤ 5%
Sulphated Ash: ≤ 5%
Heavy Metal: ≤ 10PPM
Total microbacterial count: NMT 1000cfu/g
Salmonella: NMT100cfu/g
Total Yeast & Mold: Negative
E. Coli.: Negative

Verapamil hydrochloride is a medication used for the treatment of high blood pressure, angina (chest pain from not enough blood flow to the heart), and supraventricular tachycardia.It may also be used for the prevention of migraines and cluster headaches.

 

Company Profile

Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.