Product Name:	Cefonicid sodium
Synonyms:	disodium(6r,7r)-7-[[(2r)-2-hydroxy-2-phenyl-acetyl]amino]-8-oxo-3-[[1-(sulfonatomethyl)tetrazol-5-yl]sulfanylmethyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate;CEFONICIDDISODIUM;CEFONICIDSODIUM;5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLICACID,7-[(HYDROXYPHENYLACETYL)AMINO]-8-OXO-3-[[[1-(SULFChemicalbookOMETHYL)-1H-TETRAZOL-5-YL]THIO]METHYL]-,DISODIUMSALT;CEFONICIDSODIUM[5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CARBOXYLICACID,7-[(HYDROXYPHENYLACETYL)AMINO]-8-OXO-3-[[[1-(SULFOMETHYL)-1H-TETRAZOL-5-YL]THIO]METHYL]-,DISODIUMSALT];CEFONICIDDISODIUMSALT;CefonicidDisodiumC18H16N6Na2O8S3;CefonicidSodium(Sterile)
CAS No.	61270-78-8
Formula:	C18H16N6Na2O8S3
Formula Weight:	586.53
Appearance:	Powder
Color:	White
Solubility:	DMSO (Slightly), Me thanol (Slightly)
Storage:	2-8°C
Standard:	USP/IH

Item	Standard		Test Results
Identification	A.H-NMR:Comply with the structure		Complies
	B.LC-MS:Comply with the structure		Complies
	C.The IR spectrum of sample should be identical with that of reference standard;		Complies
	D.HPLC-ESI-MS The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.		Complies
Crystallinity	meets the requirements.		Complies
Loss on drying	≤2.0%		0.19%
Heavy metals	≤10 ppm		<10ppm
Water	≤1.0%		0.1%
Sulphated ash	≤0.5%, determined on 1.0 g.		0.009%
Related substances	Unspecified impurities: for each impurity	≤0.10%	<0.10%
	Total Impurity	≤0.5%	0.18%
Purity	≥99.0%		99.7%
Assay	99.0%~101.0% (anhydrous substance).		99.8%
Microbiological Analysis
Total plate count	≤1000cfu/g		Complies
Yeast and Moulds	≤100cfu/g		Complies
E. Coli.	Absent		Negative

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