| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Cefuroxime sodium is a second-generation cephalosporin antibiotic. The antibacterial activity against Gram-positive cocci is similar or slightly worse than the first-generation cephalosporin, but the β-lactamase produced by Staphylococcus and Gram-negative bacilli is quite stable. Methicillin-resistant Staphylococcus, Enterococcus and Listeria are resistant, and other positive cocci (including anaerobic bacteria) are sensitive to this product. The antibacterial activity against Staphylococcus aureus is worse than that of cefazolin. It has strong antibacterial activity against Haemophilus influenzae, and Escherichia coli and Proteus mirabilis are sensitive to this product; Proteus mirabilis, Citrobacter and Acinetobacter have poor sensitivity to this product, Sharay Most of the genus are resistant, and Pseudomonas aeruginosa, Campylobacter and Bacteroides fragilis are resistant to this product.
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Other name: Sodium [6R-[6a,7b(Z)]]-3-[[(aminocarbonyl)oxy]methyl]-7-[2-furyl(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate CAS NO.: 56238-63-2 MF: C16H15N4NaO8S MW: 446.37 EINECS NO.: 260-073-1 InChI: 1S/C16H16N4O8S.Na/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20;/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24);/q;+1/p-1/b19-9-;/t10-,14+;/m1./s1 Appearance: White or faintly yellow powder |
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Test items |
Specifications |
Results |
|
Description |
White or faintly yellow powder |
Conforms |
|
Identification |
By HPLC |
Conforms |
|
|
It responds to the tost of sodium |
Conforms |
|
PH |
Between 6.0 and 8.5 |
6.9 |
|
Water |
Not more than 3.5% |
0.026 |
|
Residual solvents |
Ethanol not more than 0.50% |
Conforms |
|
|
Acctone not more than 0.50% |
Conforms |
|
Particulate mater |
Partiicles>25um:not more than 600part/g |
244 |
|
Sterllity |
It complies with the test for sterility |
Conforms |
|
Bacterial endotoxins |
Loss than 0.10EU/mg |
Conforms |
|
Assay |
855ug/mg to 1000ug/mg |
Conforms |
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