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CAS No:56-95-1; 206986-79-0
EINECS No: 200-302-4
Molecular Formular: C22H30Cl2N10.2(C2H4O2)
Molecular Weight: 625.55
Appearance: White crystalline powder
Grade: Medicine Grade
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Contents |
Specifications |
Results |
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Characteristics |
A white or yellowish white powder, odorless or almost, a bitter taste |
White crystalline powder |
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Identification |
(1) The positive reaction |
Complies |
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(2) The positive reaction |
Complies |
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(3) The strongest sorption at wavelength of 259nm |
The strongest sorption at wavelength of 260nm |
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(4) The positive reaction |
Complies |
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Inspection |
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p-Chloroaniline |
≤0.05% |
0.02% |
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Related Substance |
Complies |
Complies |
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Loss on Drying |
≤3.5% |
1.0% |
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Sulphated Ash |
≤0.1% |
0.01% |
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Assay |
≥97.5% of Chlorhexidine Acetate(on dried basis) |
99.3% |
Chlorhexidine acetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action. Aqueous solutions of chlorhexidine are most stable within the pH range of 5-8. Above pH 8.0 chlorhexidine base is precipitated and in more acid conditions there is gradual deterioration of activity because the compound is less stable. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
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