| Customization: | Available |
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| Powder: | Yes |
| Customized: | Non-Customized |
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Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.
| Chemical Name | gabapentin |
|---|---|
| Synonyms |
NEURONTIN;GABAPENTINE;2-(1-(Aminomethyl)cyclohexyl)acetic acid;GABAPENTIN;Gababentin;Expand |
| CAS No. | 60142-96-3 |
| Molecular Formula | C9H17NO2 |
| Molecular Weight | 171.23700 |
| PSA | 63.32000 |
| LogP | 2.07060 |
Gabapentin is an anti-epileptic drug, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in
the cause of seizures and some types of pain. Gabapentin is also used to treat neuropathic pain (nerve pain) caused by herpes
virus or shingles (herpes zoster) in adults.
Product Name: Gabapentin
Synonyms: NEURONTIN;GABAPENTINE;GABAPENTIN HYDROCHLORIDE;GABAPENTIN;GOE-3450;(1-AMINOMETHYL-CYCLOHEXYL)-ACETIC ACID;1-(AMINOMETHYL)CYCLOHEXANEACETIC ACID
CAS: 60142-96-3
MF: C9H17NO2
MW: 171.24
EINECS: 262-076-3
Melting point: 162°C
Boiling point: 314.4±15.0 °C
Storage temp.: Desiccate at +4°C
Description:
Gabapentin was introduced in 1993 in the UK and early 1994 in the USA as an adjunctive therapy in the treatment of refractory partial seizures and secondarily generalized tonic-clonic seizures. Although being a lipophilic analog of the neurotransmitter GABA, gabapentin appears to exert its anticonvulsive function by a GABA receptor independent mechanism, possibly involving the L-system amino acid transporter protein. Gabapentin easily crosses the blood brain barrier and exhibits a favorable pharmacokinetic profile with high tolerability.
It does not interfere with the metabolism of other concomitant administered antiepileptic drugs, thus having a low potential for drug interactions. Studies are currently underway for the use of gabapentin as mono-therapy for the treatment of various seizures.
Gabapentin is structurally similar to GABA (sc-203053; γ-aminobutyric acid) and is reported in various research studies to increase GABA concentrations within the brain.
Gabapentin is also noted to bind to a novel site on voltage-sensitive Ca2+ channels.
Additionally, Gabapentin is reported to demonstrate inhibition of dopamine release from caudate nucleus, preventneuronal cell death, and is antinociceptive.
Gabapentin is an anti-epileptic medication, also called an anticonvulsant. It affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain.
Gabapentin is used in adults to treat nerve pain caused by herpes virus or shingles (herpes zoster).
Amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.
Packaging & Delivery
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Package
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1kg/bag ,25kg/bag;25kg/drum; customize as customer's equirements.
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Transit
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Fedex, TNT,DHL,EMS,and so on.
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Shipping port
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Shanghai/Tianjin/Dalian/Beijing/Xi'an
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Lead Time
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1-2 working days upon received the payment
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For mass orders, it will be delivered by air or sea. Depending on your location, please allow 1-5 business days for your order to arrive. For small order, please expect 3-7 days by UPS DHL EMS. For mass order, please allow 5-8 days by Air, 15-30 days by Sea. |
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Company Information
Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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