Factory Supply Top Quality 284461-73-0 Sorafenib

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Mf: C21h16clf3n4o3
• MW: 464.82
• Einecs: 608-209-4
• Melting Point: 202-204 C
• Transport Package: 25kg
• Specification: standard
• Trademark: QDSIGMA
• Origin: China
• Production Capacity: 50000000

Product Description

 

Sorafenib (CAS 284461-73-0) is one anti-cancer drug. Sorafenib (CAS 284461-73-0) can be used in the treatment of primary kidney cancer, and hepatocellular carcinoma. Sorafenib (CAS 284461-73-0) has been formulated into finished dosage forms and marketed under the brand name Nexavar by Bayer and Onyx Pharmaceuticals.
Sorafenib (CAS 284461-73-0) is one API approved by EU and other authorities for the treatment of anti-cancer.

 

Specification of Sorafenib:

Test Items	Specification	Results
Description	White to off white crystalline powder	Comply
Melting point	166-170°C	167.3-168.1°C
Identification	Positive reaction	Positive reaction
Related substances	≤1.0%	0.16%
Loss on drying	≤0.5%	0.06%
Residue on ignition	≤0.1%	0.02%
Chloride	≤0.014%	<0.014
Heavy Metals	≤20ppm	<20ppm
Clarity of solution	Conform to standard	Complies
Microbial Limit	≤20ppm	<20ppm
Assay	≥99.0%	99.12%

 

1. Sorafenib is a novel multi-targeted antitumor drug that acts on both tumor cells and tumor blood vessels. It has dual anti-tumor effects: it can directly inhibit tumor cell proliferation by blocking the cell signaling pathway mediated by RAF/MEK/ERK, and indirectly inhibit tumor cell growth by blocking the formation of tumor neovascularization through inhibiting VE GF and platelet-derived growth fact or (PD GF) receptors.
2. Sorafenib is a novel multi-targeted oral drug for the treatment of tumors
3. Multiple kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis. Antineoplastic.

Company Profile

Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.