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| Appearance: | white to off-white crystalline powder |
| Molecular Weight: | 339.36 |
Density:
1.336 g/cm3
Boiling Point:
438.7 °C at 760 mmHg
Melting Point:
125ºC
Flash Point:
219.1 °C
Storage Temperature:
2-8°C
Refractive index:
1.497
Solubility:
DMSO Solubility : ~44 mg/mL
Biological Activity:
Anticonvulsant. Antagonizes GluR5 kainate receptors (IC 50 = 0.46 μ M), acts as a positive allosteric modulator of GABA A receptor-mediated currents, inhibits Na v channels (IC 50 = 48.9 μ M) and inhibits L-type Ca 2+ channels. Also inhibits carbonic anhydrase (CA) (K i values are 0.1 and 0.2 μ M at rat CA II and CA IV respectively), which lowers intracellular neuronal pH.
Stability:
Stable if stored as directed.
Usage:
Used as an anticonvulsant
Company Information
Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
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