Pharmaceutical API Lovastatin CAS No. 75330-75-5

• Customization: Available
• Powder: Yes
• Customized: Non-Customized
• Model NO.: 75330-75-5
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Appearance: White Powder
• Storage Method: Store in a Cool and Dry Place
• MW: 404.54
• Einecs: 616-212-7
• Transport Package: 25kg/Drum
• Specification: standard
• Trademark: QDSIGMA
• Origin: China
• Production Capacity: 50000000

Product Description

Application

Product name:	Lovastatin
CAS:	75330-75-5
Chemical Properties:	White Solid
Molecular Formula:	C24H36O5
Molecular Weight:	404.54
Uses:	An antihypercholesterolemic agent. A fungal metabolite, which is a potent inhibitor of HMG-CoA reductase antiarrhythmic Lovastatin (mevinolin) is a metabolite first isolated from Monascus ruber and later found in several other fungal species. Lovastatin is a potent inhibitor of HMG-CoA. HMG-CoA reductase is the rate-controlling enzyme of the mevalonate pathway, responsible for the biosynthesis of cholesterol. Lovastatin was developed as a drug as a hypolipemic agent. anti-hyperlipoproteinemic, 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor
Biological Activity	Potent, competitive inhibitor of HMG-CoA reductase (K i = 0.6 nM) therefore decreases cholesterol biosynthesis, in vitro and in vivo . Decreases CDK2, 4, 6 and cyclin E levels and induces G1 arrest and apoptosis in tumor cell lines in vitro .

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Company Information 

Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
 

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