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Name: Adipotie
CAS No.: 121062-08-6
MF: C78H111N21O19
Sequence: CKGGRAKDC-GG-D(KLAKLAK)2
Molecular formula: C111H204N36O28S2
Molar Mass: 2555.22 g/mol
Peptide Sequence: H-Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys-Gly-Gly-Asp-(Lys-Leu-Ala-Lys-Leu-Ala-Lys)2
| Item | Specifications |
| Appearance | White powder. |
| Purity | 99%min |
| Boiling point | 1802.9±65.0ºC at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Refractive index | 1.576 |
| Flash point | 1044.2±34.3ºC |
| Storage condition | 2-8ºC |
| Shelf life | 2 years |
Purity: 98%min
Appearance : White to off-white crystalline powder or lumps
Specific Optical Rotation (c=0.5,10% HAc) :-50.0~-60.0°
Water Content(Karl Fischer) : ≤5.0%
Acetate Content(by HPLC) : ≤15.0%
Amino Acid Composition : ±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N) : ≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Adipotide is that is intended to help you in the reduction of weight. It is a product that is meant to help in weight reduction through killing the fat cells in your body. This is because when the fat cells die, it decreases the volume within the subcutaneous fat, which leads to a reduction in fatty tissues, reduced BMI and reduced waist circumference.
Aditpotide is an experimental weight loss peptidomimetic with the amino acid sequence CKGGRAKDC-GG-D(KLAKLAK)2, which has been developed by researchers in the United States in an effort to fight obesity. Peptidomimetics are small protein-like chains designed to mimic a peptide. The peptides called Adipotide has been developed by U.S. researchers in the fight against the obesity. This experimental treatment has reduced by 11% the weight of the treated monkeys by reducing fatty tissue, the BMI, and waist circumference.
Selected Studies:
Studies done by Mikhail G Kolonin et al have shown that adipotide has the capabilities of inducing apoptosis of the vascular bed of the white adipocytes in mice, and this resulted in the normalization of metabolic processes.
A related study conducted by Kirstin F. Barnhart et al on monkeys have shown that adipotide induced apoptosis of the vascular bed of the white adipocytes with a resultant weight loss and normalization of ins ulin function. These studies show that adipotide does cause weight loss by inducing selective apoptosis.
Adipotide and Fat Loss / Weight Loss:
Adipotide is an experimental treatment that prevents the blood supply to fat cells. This has helped obese monkeys to lose on average 11% of their body weight in four weeks, perhaps opening the way for therapy in humans, according to a recent research study. The study, published in the journal Science Translational Medicine , shows that body mass index and waist circumference of the rhesus monkeys were reduced.
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