Factory Price CAS 88150-42-9 99% Amlodipine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: 99 Amlodipine
• Suitable for: Elderly, Adult
• State: Solid
• Purity: >99%
• Mf: C20h25cln2o5
• MW: 408.88
• Einecs: 1308068-626-2
• Melting Point: 178-179 C
• Transport Package: 25kg/Drum, 1kg/Bag or According to Customer Reques
• Specification: 99
• Trademark: QDSIGMA
• Origin: China

Product Description

 

Product name	Amlodipine
Cas No.	88150-42-9
Molecular Formula	C20H25ClN2O5
Appearance	Yellow crystalline powder

 

Amlodipine is a long-acting calcium channel blocker.Target: Calcium ChannelAmlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the movement of calcium ions into vascular smooth muscle cells and cardiac muscle cells. Experimental data suggest amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac muscle and vascular smooth muscle are dependent upon the movement of extracellular calcium ions into these cells through specific ion channels. Amlodipine inhibits calcium ion influx across cell membranes selectively, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. Negative inotropic effects, or decreased heart muscle contractility, can be detected in vitro, but such effects have not been seen in intact animals at therapeutic doses. Serum calcium concentration is not affected by amlodipine. Within the physiologic pH range, amlodipine is an ionized compound (pKa = 8.6), and its interaction with the calcium channel receptor is characterized by a gradual rate of association and dissociation with the receptor binding site, resulting in a gradual onset of effect. Amlodipine is a peripheral arterial vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure.

1.Amlodipine is indicated for the treatment of chronic stable angina; it may be used alone or in combination with other antianginal agents.
2.Amlodipine is indicated for the treatment of confirmed or suspected vasospastic angina. It may be used alone or in combination with other antianginal agents. 
3.Amlodipine is indicated for the treatment of hypertension; it may be used alone or in combination with other antihypertensive agents. 
4.Amlodipine is used in the treatment of hypertension, chronic stable angina pectoris, and vasospastic angina.

Company Profile

Qingdao Sigma Chemical Co., Ltd.is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co., Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

 

Qingdao Sigma Chemical Co., Ltd has become the "Top 500 Chinese manufacturing companies",

"Top 20 of global chemical sales".Qingdao Sigma Chemical Co., Ltd has 21 subsidiaries and holding companies.
 

FAQ

Q1: Are you a manufacturer?
Answer: Yes, we are factory founded on 2002.
 
Q3:Which kind of payment terms do you accept?
For small order,you can pay by T/T,Western Union or Paypal,nomal order by T/T to our company account
 
Q4:Can you give me a discount price?
Surely,It depend on your qty
 
Q5:How can i get a sample?
free samples is available,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.
 
Q6: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
 
Q7:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.