High Quality Medical Grade 41354-29-4 Cyproheptadine Hydrochloride

Powder: Yes
Customized: Non-Customized
Certification: GMP, HSE, ISO 9001, USP, BP
Suitable for: Elderly, Children, Adult
State: Powder
Purity: >99%
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Basic Info.

Specification
standard
Trademark
QDSIGMA
Origin
China
Production Capacity
50000000

Product Description

Cyproheptadine Hydrochloride

 

Product Description

  

Product Name Cyproheptadine Hydrochloride
CAS 41354-29-4
Appearance White Crystalline powder
Specification 99%
Test method HPLC/UV

Cyproheptadine is a first-generation antihistamine with additional anticholinergic, antiserotonergic, and local anesthetic properties.

Cyproheptadine is used to treat allergic reactions (specificallyhay fever).

Has shown effectiveness in the treatment of nightmares including nightmares related to post traumatic stress disorder. 

Items

Acceptance criteria

Results

Character

Appearance: White or almost white powder.

Almost white powder

Solubility: Slightly soluble in water, freely

soluble in dilute acetic acid and in methanol,

slightly soluble in alcohol.

Complies

Identification

A.Specific optical rotation: -30.0º~-33.5º

(dried substance)

-33.3º

B.Infrared absorption spectrophotometry:

The IR spectrum is consistent with that

obtained with Levodropropizine CRS.

Complies

Tests

pH

9.2~10.2

9.4

Impurity B and related

substances

Impurity B: ≤ 0.5%

≤ 0.1%

Any other impurity: ≤ 0.1 %

≤ 0.1%

Total impurities: ≤ 0.6 %

≤ 0.1%

Impurity C

≤ 5 ppm

≤ 5ppm

Enantiomeric purity

Impurity A: ≤ 2 %

0.2 %

Loss on drying

≤ 1.0 %.

≤ 0.1%

Sulphated ash

≤ 0.2 %

≤ 0.1%

Assay

98.5%~ 101.0%(dried substance)

99.7%

Conclusion

The product meets the specification of EP7.0

 

Functions

Has been used in the management of moderate to severe cases of serotonin syndrome (a complex of symptoms associated with the use of serotonergic drugs, such as selective serotonin reuptake inhibitors and monoamine oxidase inhibitors), and in cases of hyperserotoninaemia resulting from a serotonin producing carcinoid tumour

 

Can also be used as a preventive measure against migraine in children and adolescents.

Can relieve SSRI-induced sexual dysfunction and drug-induced hyperhidrosis (excessive sweating).

Also used in the treatment of cyclical vomiting syndrome and to stimulate the appetite.

 

Company Information
 

Qingdao Sigma Chemical Co.,Ltd is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

The aim of Qingdao Sigma Chemical Co.,Ltd is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.



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